McIlroy, Donald, Warren tied for lead in Dubai

DUBAI, United Arab Emirates (AP) ? Rory McIlroy shot a 5-under 67 Friday and was tied for the lead with Luke Donald and Marc Warren after two rounds of the season-ending Dubai World Championship.

McIlroy, the top-ranked golfer, has already won the money titles on the European and PGA tours. He was one stroke in front at 11-under 133 with Donald (68) and 189th-ranked Warren (67).

Sergio Garcia, playing for the first time since laser eye surgery, matched the course record with a 64 to leave him four shots behind.

McIlroy's round could have been even better, but he missed several makeable putts on the front nine and an eagle putt roll past the hole at No. 14.

"I continued driving the ball well today and gave myself plenty of opportunities," McIlroy said. "Missed a couple of short ones on the front nine for birdies. But apart from that, it was a very solid round of golf."

Garcia started with four birdies on his first five holes and then had a string of birdies at the turn before holing a long putt for eagle on No. 14. But he shot into the water on No. 16 for a triple-bogey before recovering to finish with a birdie and eagle.

"Coming back from a long break, so trying to get some good vibrations going and I managed to finish better than that," Garcia said.

Donald joined McIlroy and Warren at 11 under with a short birdie putt on the 18th. Warren had a chance take the outright lead, but was short on his 12-foot putt on the 18th.

"Obviously, haven't dropped a shot in 36 holes, so feel good about that," said Donald, who finished with four birdies in a bogey-free round. "I had some opportunities, 10-foot, 15-footers on a few holes that I just misread. But that was a solid round of golf."

Donald said he wasn't getting his approach shots as close to the pin as the first day, but made up for it with the putter, including a difficult birdie on No. 9 and nice par save on No. 12.

"When I have myself a little bit of trouble out on the course, I was able to recover with the putter," Donald said.

Warren, who has not won a tournament since 2007, matched the second-ranked Donald's opening birdie and had five more, including a 12-footer on the 16th to move him into a tie with McIlroy.

"It was nice to be the Scot in the pack with the Englishman and the Northern Irishman," Warren said. "It's great to be in contention with guys like that. Looking down the leaderboard, it's a high-quality leaderboard and doesn't get any better anywhere in the world really."

Two South Africans were a stroke behind at 134 ? Louis Oosthuizen, the 2010 British Open champion, shot a 67 and four-time tour winner Branden Grace had a 65.

Charl Schwartzel (67) and Richie Ramsay (68) were two shots off the pace, followed by another 10 players three strokes behind.

Several big names faltered, including fourth-ranked Lee Westwood (74). Two shots off the lead after the first round, Westwood bogeyed the 12th and 16th and then double-bogeyed the par-3 17th to fall eight shots off the lead.

Padraig Harrington, also two shots back after the first round, was five behind after a 71.

Source: http://news.yahoo.com/mcilroy-donald-warren-tied-lead-dubai-184352438--spt.html

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Patty Murray likely to be a key voice in Senate on budget deal (Washington Post)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/265951181?client_source=feed&format=rss

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Tiny probes shine brightly to reveal the location of targeted tissues

Wednesday, November 21, 2012

Called BRIGHTs, the tiny probes described in the online issue of Advanced Materials on Nov. 15, bind to biomarkers of disease and, when swept by an infrared laser, light up to reveal their location.

Tiny as they are, the probes are exquisitely engineered objects: gold nanoparticles covered with molecules called Raman reporters, in turn covered by a thin shell of gold that spontaneously forms a dodecahedron.

The Raman reporters are molecules whose jiggling atoms respond to a probe laser by scattering light at characteristic wavelengths.

The shell and core create an electromagnetic hotspot in the gap between them that boosts the reporters' emission by a factor of nearly a trillion.

BRIGHTs shine about 1.7 x 1011 more brightly than isolated Raman reporters and about 20 times more intensely than the next-closest competitor probe, says Srikanth Singamaneni, PhD, assistant professor of mechanical engineering and materials science in the School of Engineering & Applied Science at Washington University in St. Louis.

Goosing the signal from Raman reporters

Singamaneni and his postdoctoral research associate Naveen Gandra, PhD, tried several different probe designs before settling on BRIGHTS.

Singamaneni's lab has worked for years with Raman spectroscopy, a spectroscopic technique that is used to study the vibrational modes (bending and stretching) of molecules. Laser light interacts with these modes and the molecule then emits light at higher or lower wavelengths that are characteristic of the molecule,

Spontaneous Raman scattering, as this phenomenon is called, is by nature very weak, but 30 years ago scientists accidently stumbled on the fact that it is much stronger if the molecules are adsorbed on roughened metallic surfaces. Then they discovered that molecules attached to metallic nanoparticles shine even brighter than those attached to rough surfaces.

The intensity boost from surface-enhanced Raman scattering, or SERS, is potentially huge. "It's well-known that if you sandwich Raman reporters between two plasmonic materials, such as gold or silver, you are going to see dramatic Raman enhancement," Singamaneni says.

Originally his team tried to create intense electromagnetic hot spots by sticking smaller particles onto a larger central particle, creating core-satellite assemblies that look like daisies.

"But we realized these assemblies are not ideal for bioimaging," he says, "because the particles were held together by weak electrostatic interactions and the assemblies were going to come apart in the body."

Next they tried using something called Click chemistry to make stronger covalent bonds between the satellites and the core.

"We had some success with those assemblies," Singamaneni says, "but in the meantime we had started to wonder if we couldn't make an electromagnetic hot spot within a single nanoparticle rather than among particles.

"It occurred to us that if we put Raman reporters between the core and shell of a single particle could we create an internal hotspot."

That idea worked like a charm.

A rainbow of probes carefully dispensing drugs?

The next step, says Singamaneni, is to test BRIGHTS in vivo in the lab of Sam Achilefu, PhD, professor of radiology in the School of Medicine.

But he's already thinking of ways to get even more out of the design.

Since different Raman reporter molecules respond at different wavelengths, Singamaneni says, it should be possible to design BRIGHTS targeted to different biomolecules that also have different Raman reporters and then monitor them all simultaneously with the same light probe.

And he and Gandra would like to combine BRIGHTS with a drug container of some kind, so that the containers could be tracked in the body and the drug and released only when it reached the target tissue, thus avoiding many of the side effects patients dread.

Good things, as they say, come in small packages.

###

Washington University in St. Louis: http://www.wustl.edu

Thanks to Washington University in St. Louis for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/125407/Tiny_probes_shine_brightly_to_reveal_the_location_of_targeted_tissues

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$2,500 Reward Offered After Puppy Tied To Truck, Dragged Down ...

Posted on: 3:44 pm, November 21, 2012, by Staff Writer, updated on: 03:49pm, November 21, 2012

ST. LOUIS, MO (KTVI)? The Humane Society of Missouri is offering an award after a puppy was tied to the back of a truck and drug along Interstate 55.

The Humane Society of Missouri Animal Cruelty Task Force dispatched an investigator to the scene and found the driver of the truck distraught by the situation. He stated that he did not know the animal or how it became tied to the back of his vehicle. He was alerted to the incident by another driver who called the police and signaled him that something was wrong. He pulled over and discovered the dog.

The puppy, a five and a half month old brown, male pit bull, was in shock and is suffering from severe and traumatic injuries including exposed tissue and bones. The puppy is being treated at the Humane Society of Missouri Maryland Heights facility. He had a collar and leash, but no ID tag or microchip were found.?

The Humane Society of Missouri is offering a $2,500 reward for information leading to the arrest and conviction of the person or persons responsible. HSMO also is looking for the owner of the puppy. If you have any information call 314-647-4400.?

Animal Abuse Task Force Charges Man For Shooting, Strangling?Dog

Source: http://fox2now.com/2012/11/21/2500-reward-offered-after-puppy-tied-to-truck-dragged-down-highway/

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Benchmarks Can Reveal the Finance Department's Achilles Heel ...

About the panel

Stephen Baker is the author of The Numerati & a journalist with 20 years of experience at BusinessWeek. More??

Paul Barsch directs professional services marketing programs for Teradata and has more than fifteen years of information... More??

Gary Cokins is an internationally recognized expert, speaker, and author. More??

Jill Dych? is an internationally recognized author, speaker, and business consultant. More??

Themos Kalafatis has worked as a consultant for Data Mining, Text Mining, Information Extraction and Data Quality for over a decade. More??

James Taylor is CEO and Principal Consultant at Decision Management Solutions and a leading expert in decision management. More??

Source: http://smartdatacollective.com/david-kasabian/86256/benchmarks-can-reveal-finance-departments-achilles-heel

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Analysis: China courts friends in region; for others a show of strength

PHNOM PENH/BEIJING (Reuters) - When U.S. President Barack Obama and more than a dozen leaders arrived in Cambodia for a regional summit meeting this week, only one of them was feted with banners strung from the venue gates.

"Welcome Prime Minister Wen Jiabao!" one proclaimed. "Long live the People's Republic of China!" read another.

As the leaders left, the green-and-white banners were still festooned outside Phnom Penh's Peace Palace, a fitting reminder of China's powerful and growing clout as Beijing uses its influence - and money - to win friends and frustrate those uneasy about its sweeping territorial claims and rising military strength.

"Some states are easily swayed by money. If they see cash, they easily throw away their principles," said one Asian diplomat at the East Asia Summit, which included heads of state from 10 Southeast Asia countries and counterparts from the United States, China, Japan and other Asia-Pacific nations.

"China has been throwing its weight around and buying the loyalties of some Asian states."

A prime example is Cambodia, whose prime minister, Hun Sen, helped China to notch up a succession of diplomatic victories at the summit. China stalled debate on a resolution of maritime disputes in the South China Sea, rebutted attempts by Southeast Asian nations to start formal talks on the issue and avoided any rebuke from Obama over territorial ambitions. Commentators declared China a clear summit winner.

A closing statement by Hun Sen, this year's chair of the 10-member Association of Southeast Asian Nations (ASEAN), made no mention of the South China Sea, another victory for China's attempts to prevent multilateral talks on the dispute.

China has poured investments and loans into Cambodia in recent years, becoming its biggest trade partner and bilateral creditor. Cambodia's debt to China now totals at least $4.7 billion, about a third of its economy.

The price of that largesse has become clear this year, say analysts, as Cambodia has used its powers as ASEAN chair to restrict debate over the vexed issue of China's maritime claims, dividing the group and infuriating U.S. ally the Philippines.

The 45-year-old ASEAN group has been built on a foundation of unanimity and unity, but that has unraveled as it struggles to cope with its biggest security challenge. In July, a meeting of the region's foreign ministers broke down in unprecedented acrimony and failed to agree a communique for the first time.

This week's ASEAN meetings again deteriorated into bad-tempered sniping and came close to a breakdown when Hun Sen adopted a draft statement saying there was a consensus not to "internationalize" the South China Sea dispute beyond ASEAN and China.

The Philippines, which sees its alliance with the United States as a crucial check on China's claims at a time when Washington is shifting its military focus back to Asia, made a formal protest to Cambodia and succeeded in having that clause removed from the final statement.

China then poked fun at Manila's assertion that there had been no consensus. Eight out of 10 leaders had agreed not to internationalize the dispute, meaning there was a consensus, said Qin Gang, a Chinese foreign ministry spokesman.

"I suggest that people when attending the EAS (East Asia Summit) meetings have to be very good at mathematics," he said.

"That's 10 minus two, so which is bigger?"

NAVAL BUILDUP

Beijing claims a vast U-shaped line around the South China Sea that brushes up against the coasts of the Philippines, Vietnam, Brunei and Malaysia. The area is thought to hold vast, untapped reserves of oil and natural gas, and naval flashpoints between Chinese vessels and the Philippine and Vietnamese navy have become increasingly common.

Hopes for a diplomatic resolution within the ASEAN-China framework look bleak in the next two years as tiny Brunei and then Myanmar take up the chairmanship of the group.

Cambodia, like fellow "Mekong" countries Laos and Myanmar, has been rapidly pulled into China's economic orbit through rocketing trade and investment ties.

It has become customary for Chinese officials to arrive in Cambodia bearing "gifts", such as the $100 million investment that Wen announced on his arrival this week to build the emerging country's biggest cement plant. China has moved nimbly to set up free trade deals with Southeast Asia nations and has played a dominant role in financing and building big infrastructure projects in Laos, Cambodia, and Myanmar.

After the summit, Wen visited Thailand where he signed an understanding to buy rice, which should strongly lift Beijing's standing with a government that is a close ally of the United States. Bangkok has built up record stockpiles of 14 million tonnes of milled rice after a populist program to pay farmers more for their crops made exports unprofitable.

If diplomatic efforts stall, China's options to back its claims with force if needed are steadily growing with a military budget that outstrips the combined spending of Southeast Asia.

As China ushered in a new generation of leaders this month, outgoing President Hu Jintao made a pointed reference to strengthening China's naval forces, protecting maritime interests, and the need to "win local war."

"We should make active planning for the use of military forces in peacetime, expand and intensify military preparedness, and enhance the capability to accomplish a wide range of military tasks, the most important of which is to win local war in an information age," Hu said.

Besides the South China Sea, China is embroiled in a dispute with Japan, also a close U.S. ally, over islands in the East China Sea.

China's stance is that it is not trying to become an offensive naval power, but wants to secure its energy imports and boost development of maritime natural resources, which are expected to represent 10 percent of its economy by 2015.

But it is also wary of being encircled as the United States refocuses its military clout on Asia in what Obama has called a "pivot" back to the region as wars in the Middle East wind down.

"It is absolutely (a buildup)," said Ruan Zongze, deputy director of the China Institute of International Studies, the think-tank of the Chinese Foreign Ministry.

"No matter what kind of narrative you use, the reality is that America in the past three years has been putting greater emphasis or focus on the west Pacific. That raises a lot of questions for China."

China launched its first aircraft carrier in September, increasing its ability to project forces deeper into "blue-water" maritime territory. Bought from Ukraine ostensibly to use as a floating casino, the Chinese navy spent years refurbishing the carrier, which is undergoing sea trials. It also test-flew two types of stealth fighters this year, the second one last month - a smaller, more maneuverable model believed to be designed to be deployed on an aircraft carrier.

"China has ambitions to become the premier military power among its regional peers, and a serious threat to U.S. maritime primacy in the Asia Pacific," said Sam Roggeveen, an Asian defense analyst with the Lowy Institute in Sydney.

Roggeveen added that if China were to deploy more than one carrier and equip them with high-performance stealth fighters, "it would become the pre-eminent regional maritime power, with the ability to coerce neighbors in disputes in which the U.S. prefers not to get involved".

(Additional reporting by James Pomfret and Manuel Mogato in PHNOM PENH; Editing by Jason Szep and Raju Gopalakrishnan)

Source: http://news.yahoo.com/analysis-china-courts-friends-region-others-show-strength-092621618.html

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Former Elmwood resident releases historical novel about home's ...

Former Elmwood resident Ann Small Niess wrote a historical novel to tell the stories of ghosts that haunted her childhood home. (SUBMITTED)

Growing up, Ann Small Niess didn?t talk much about the ghosts that lived in her family?s house in Spring Garden Township.

?I never told anybody outside the family about it as a kid,? she said. ?I was an only child and I wanted to make friends.?

Those voices from beyond the grave didn?t stay silent forever, though.

Decades later, the 89-year-old, who now lives in Naples, Fla., remembered her family?s encounters in Elmwood Mansion.?Using a journal her mother had kept about the ghosts and tapping into her own memories, Niess recently completed an historical novel, ?Hidden Secrets of Jacob?s House,? in which she imagines the back stories for each of Elmwood?s spirits.

Read the full story from Book Buzz, www.yorkblog.com/books.

I'm the books editor and a multiplatform copy editor at the York Daily Record / Sunday News. I dabble in green living, food, gardening and -- of course -- all things books-related. Have an idea, suggestion or comment? Email me at schain@ydr.com. This entry was posted in Books, Books to read and tagged ann small niess, author, childhood, elmwood house, elmwood mansion, florida, ghosts, hidden secrets of jacob's house, history, naples, novel, spirits, spring garden township, York. Bookmark the permalink.

Source: http://www.yorkblog.com/smart/2012/11/20/former-elmwood-resident-releases-historical-novel-about-homes-ghosts/

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